Abstract
AbstractA nonsteroidal estrogen antagonist, CI‐628, was administered orally to female beagle dogs on days 1–15 following mating. Dosages of 0.5, 1, 2, and 5 mg/kg effectively blocked pregnancy; six litters were whelped after 0.125 or 0.25 mg/kg in which various defects were present in pups of three litters.
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Schedule a callMore From: Birth Defects Research Part A: Clinical and Molecular Teratology
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