Canine Peyer's patches: macroscopic, light microscopic, scanning electron microscopic and immunohistochemical investigations.

Abstract

In 1928, Carlens reported on his detailed investigations of the morphology and ontogeny of lymphoid tissue in the intestinal tract of large domestic animals (1). He observed that the morphology and development of the ileal Peyer’s patch (PP) was different from the PP in the rest of the small intestine. Recent studies in sheep (2), cattle (3) and swine (4) have confirmed and expanded Carlens’ observations. The ileal PP has been shown to be functionally different from the jejunal PP and may represent the bursa-equivalent in sheep and cattle (3,5). In contrast, morphologic studies in mice (6), rats (7) and humans (8) do not indicate the existence of these regional differences of PP.KeywordsLamina PropriaGerminal CenterIntestinal CryptHigh Endothelial VenuleLymphoid NoduleThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.