Canine parvovirus infection in immunized and non-immunized diarrhoeic dogs

Abstract

Vaccination is the ideal and cost effective method to control the canine parvoviralgastroenteritis and both live attenuated and killed vaccines are available to control the disease in dogs. Inspite of wide spread vaccination practice, the disease has been reported in both vaccinated and unvaccinated dogs. Canine parvovirus (CPV) infection was tested in faecal and serum samples of 178 diarrhoeic dogs from Kamrup district of Assam by using ELISA. The CPV infection was recorded as 9.52% in vaccinated and 30.15% in unvaccinated dogs by sandwich ELISA with case fatality rate of 17.78%. Indirect ELISA detected 66.67% vaccinated and 33.82% unvaccinated dogs sero-positive against CPV and the antibody levels ranged from 1.00 to 2.806 with higher level of antibody in unvaccinated dogs than vaccinated dogs, which suggested the strong boosting of immunity following natural infection. The high rate of infections in both vaccinated and unvaccinated dogs indicated the need of detailed study of the field strains of the virus which may probably differ from the present vaccine strain.