Abstract
In 5 anesthetized and 5 conscious dogs, gastric blood flow was measured with 15-μ labeled microspheres. Acid secretion and regional flow under control conditions (mean blood pressure (BP) = 100 mm Hg), after 1 hr of hemorrhagic shock (mean BP = 40 mm Hg), and 60 min after re transfusion of shed blood (mean BP = 100 mm Hg) were measured. Results are expressed as mean milliequivalents per hour for acid secretion and milliliters per minute x 100 g of tissue for blood flow. These results indicate that (1) acid secretion and regional blood flow are significantly higher in conscious dogs; (2) hemorrhagic shock caused a significant reduction of acid secretion and blood flow within the gastric tissue; (3) blood flow to fundic mucosa decreases more than antral mucosa (P
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