Abstract
We describe a new Bartonella species for which we propose the name Candidatus Bartonella mayotimonensis. It was isolated from native aortic valve tissue of a person with infective endocarditis. The new species was identified by using PCR amplification and sequencing of 5 genes (16S rRNA gene, ftsZ, rpoB, gltA, and internal transcribed spacer region).
Highlights
We describe a new Bartonella species for which we propose the name Candidatus Bartonella mayotimonensis
Serum immunoglobulin G titers were positive for B. henselae and B. quintana (>1,024)
Oral doxycycline and rifampin were prescribed for treatment of presumed Bartonella endocarditis
Summary
We describe a new Bartonella species for which we propose the name Candidatus Bartonella mayotimonensis It was isolated from native aortic valve tissue of a person with infective endocarditis. We report a case of culture-negative endocarditis caused by a new Bartonella species, for which we propose the name Candidatus Bartonella mayotimonensis. PCR performed at the Mayo Clinic on resected aortic valve tissue detected part of the citrate synthase gene (gltA) of Bartonella species. DNA was used as a template in a genus Bartonella Lightcycler assay with primers and a Taqman probe specific for the internal transcribed spacer (ITS) gene [6] and in standard PCR assays specific for the 16S rRNA, ITS, rpoB, gltA, and ftsZ genes [8] Sequences from both DNA strands were determined twice for all PCR products. Phylogenetic relationships among Bartonella strains were inferred from concatenated sequences by using MEGA 2.1 software [9]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
