Abstract
The shortage of suitable donor hearts has made the selection of potential transplant recipients a critical step in the cardiac transplantation process. Appropriate patients for transplantation should have a high predicted short- and intermediate-term mortality rate despite aggressive medical therapy. Stratifying patients based on the etiology of the heart failure, left ventricular ejection fraction, functional capacity, hemodynamic measurements, the presence of arrhythmias, and neurohormonal activation is useful in defining a high-risk population. The transplant evaluation should focus on risk definition as well as on factors that increase posttransplant morbidity and mortality.
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