Abstract

We present a case of Candida dubliniensis meningitis that developed 2 months after apparently successful treatment of an episode of C. dubliniensis candidemia in a heart-lung transplant recipient in Australia. This case highlights the importance of follow-up in patients with candidemia or disseminated infection, especially in immunosuppressed patients.

Highlights

  • We present a case of Candida dubliniensis meningitis that developed 2 months after apparently successful treatment of an episode of C. dubliniensis candidemia in a heartlung transplant recipient in Australia

  • Candidemia clearance was confirmed by negative blood cultures

  • The patient was discharged from intensive care on day 14 and from hospital 52 days posttransplant, in April 2007; he was not receiving any antifungal agents on discharge

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Summary

Introduction

We present a case of Candida dubliniensis meningitis that developed 2 months after apparently successful treatment of an episode of C. dubliniensis candidemia in a heartlung transplant recipient in Australia. Candidemia clearance was confirmed by negative blood cultures A chest and abdominal computed tomography scan (on day 32 of antifungal therapy) showed a normal liver, spleen, and renal tract as well as bilateral reaccumulated pleural effusions after removal of the intercostal chest drains. The patient was discharged from intensive care on day 14 and from hospital 52 days posttransplant, in April 2007; he was not receiving any antifungal agents on discharge. The total duration of therapy for disseminated candidiasis was 40 days, consisting of caspofungin (28 days) followed by fluconazole (400 mg/day for 12 days).

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