Abstract
Background: Candida species are one of the most common causes of blood-stream infections. Although Candida albicans is the most common clinical isolate, several studies have detected a global shift in epidemiology toward non-albicans Candida species. Methods & Materials: In this study the emergence of blood-stream infections caused by Candida spp. was explored retropectively over one year period in Akdeniz University Hospital Clinical Microbiology Laboratory. A total of 164 blood cultures from 97 patients were investigated. The blood culture isolates were identified usind standard mycological methods. Organisms were identified to the species level by germ tube test and by the evaluation of morphologic properties on Corn Meal Tween 80 agar. Results: While C. albicans was the most frequently isolated species (n = 65), non-C. albicans Candida spp. included; C. parapsilosis (n = 42), C. tropicalis (n = 18), C. glabrata (n = 14), C. krusei (n = 10). Fifteen isolates could not be identified to the species level and were determined as Candida spp. Conclusion: In our study, C. albicans accounts for 39.6% of all Candida blood stream infections, although a noticeable shift toward Candida species other than C. albicans has been observed, which is important because of intrinsic or acquired antifungal resistance in several of these species.
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