Abstract

To assess the epidemiology of neonatal Candida blood stream infection. Medical records of neonates with Candida blood stream infection over 5 years (September 2010 to August 2015) were reviewed. Clinical details, species distribution and antifungal susceptibility were noted. 114 neonates developed Candida blood stream infection. Commonly isolated Candida species were C. tropicalis, C. albicans and C. parapsilosis. Susceptibility for fluconazole and amphotericin B was 86.6% and 68.3%, respectively. Central line >7 days and hospital stay >28 days were independent risk factors associated with non-albicans Candida infection. Early removal of central line, timely fungal culture and antifungal susceptibility are necessary for early and appropriate treatment and better outcome.

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