Abstract

Candida auris is an emerging multidrug-resistant fungal pathogen. Since first reported in 2009, C. auris has caused healthcare outbreaks around the world, often involving high mortality. Identification of C. auris has been a major challenge as many common conventional laboratory methods cannot accurately detect it. Early detection and implementation of infection control practices can prevent its spread. The aim of this review is to describe recommendations for the detection and control of C. auris in healthcare settings.

Highlights

  • Candida auris is an emerging multidrug-resistant fungus that has caused outbreaks of invasive infections in healthcare facilities around the world

  • Implementation of infection control practices is crucial for controlling C. auris outbreaks in healthcare settings [2]

  • Identify the species of Candida isolated from non-sterile sites when clinically indicated, when the patient resides on the facility or unit where a C. auris case has been identified, or when the patient had an overnight stay in a facility outside the United States in the past year, especially if in a country with

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Summary

Introduction

Candida auris is an emerging multidrug-resistant fungus that has caused outbreaks of invasive infections in healthcare facilities around the world. C. auris has been reported from dozens of countries from six continents and has caused outbreaks in places such as Colombia, India, South Africa, Spain, and the United States (https://www.cdc.gov/fungal/candida-auris/tracking-c-auris.html). Healthcare facilities have reported C. auris outbreaks in critically ill hospitalized patients with high crude mortality rates (30% to 72%) [1,2,3]. Risk factors for C. auris bloodstream infections (BSIs) are similar to the risk factors for other Candida species BSIs, including recent major surgical procedures, diabetes, use of broad-spectrum antibiotics, long-term hospitalizations, and the presence of devices, including breathing tubes, feeding tubes, and central venous catheters. In the United States, patients with neurologic diseases in long-term care with many devices may be at higher risk of developing invasive C. auris infections [3,4].

Candida auris Identification
Candida auris Antifungal Susceptibility Testing
Infection Control Practices
Treatment and Management of Infections and Colonization
Communication
Conclusions
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