Abstract
Because there is increased glycolysis in cancer cells, whole-body positron emission tomography (WB PET) with 18F-fluorodeoxyglucose can be used to detect cancers (figure). With its high sensitivity and ability non-invasively to survey the entire body, WB PET has potential for detecting cancers of many types with a single examination. We investigated the use of WB PET for cancer screening in individuals without symptoms. We studied members of a medical health club in Yamanashi, Japan, participating in a continuing cancer-screening programme that incorporates clinical, imaging, and immunochemical methods for the detection of cancers.
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