Abstract
To conduct a meta-analysis of epidemiologic studies to derive a pooled estimate of the association between asthma and cancer incidence and between allergy and cancer incidence. Five cohort studies and 1 case-control study of cancer incidence in asthma, 4 studies of cancer mortality in asthma, and 3 studies of cancer incidence in allergy. We searched the National Library of Medicine Gateway to identify observational studies of cancer incidence in asthma and included any case-control or cohort study of incident cancers or of cancer mortality that met the predefined inclusion criteria. There was no significant association between asthma and cancer incidence. A single large cohort study demonstrated a protective effect of asthma; the remaining cohort studies demonstrated a slightly elevated risk of cancer associated with asthma. Inconsistencies in study design features included control of smoking in analyses, use of a control group, and methods to identify asthma status. The method of asthma identification affects the validity of asthma classification and the severity of asthma examined. The inconsistency in study designs could have contributed to the variability in results and the underestimation of the impact of asthma on cancer incidence.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
