Abstract
Cancer incidence in the Dalgety Bay area of Fife, Scotland, was examined following the detection of radium-226 particles by routine radiation monitoring. The study was confounded by rapid population growth, demographic change and the relatively high socioeconomic status of the Dalgety Bay population. Health Board Primary Care Division records were used to calculate population estimates and Carstairs deprivation score was used to adjust for socioeconomic characteristics. In the period 1975-90, 211 residents were registered as having cancer compared with 214.21 expected from Scottish national rates. Of specific cancers possibly associated with radiation, the incidence of stomach, liver, lung, bone, prostate, bladder and kidney cancer and lymphoma were lower than expected while colon, rectum, pancreas, skin, breast and thyroid cancer and multiple myeloma and leukaemia were higher. There were three cases of childhood leukaemia compared with 1.22 expected. The only statistically significant differences observed were for pancreas (11 cases, O/E 2.28), lung (25 cases, O/E 0.65) and non-melanoma skin (36 cases, O/E 1.50). Stomach cancer was of borderline statistical significance (four cases, O/E 0.40). Adjustments for socioeconomic factors accounted for the apparently low incidence of stomach and lung cancer and, to a lesser extent, skin cancer, which remained of borderline statistical significance. Results in relation to pancreas cancer were unchanged. The observations of raised incidence of pancreas and skin cancer arose in the context of a survey of 17 cancer sites, from which the finding of two or more statistically significant results is not unusual (P = 0.21), and the numbers of cases involved were small. The epidemiological evidence for an association between radiation exposure and pancreas cancer risk is weak. Stronger evidence exists for an association with skin cancer. In the present study the anatomical distribution of the 36 cases was similar to that found elsewhere in Scotland.
Highlights
In 1990 routine radiation monitoring detected particles of radium-226 on the foreshore at Dalgety Bay, a small town situated on the south coast of the Fife Health Board area in east central Scotland
This paper describes an evaluation of cancer incidence rates in the Dalgety Bay area and the methods used to derive estimates of person-years-at-risk and to control for effects of socioeconomic status
In the study period 211 malignant neoplasms were registered in residents of Dalgety Bay, representing an overall rate which was not significantly different from the number expected (214.21) from age- and sex-specific Scottish natibnal rates (O/E 0.99, 95% CI 0.86-1.13) (Table II)
Summary
In 1990 routine radiation monitoring detected particles of radium-226 on the foreshore at Dalgety Bay, a small town situated on the south coast of the Fife Health Board area in east central Scotland. The contamination is thought to have been due to the disposal by burning of military aircraft in the 1940s. Some of these aircraft were equipped with night vision instruments manufactured using radium-based luminous paint. The area was surveyed by the National Radiation Protection Board (NRPB) and the detected material removed. The NRPB concluded at that time that the likelihood of a hazard to the public due to internal or external exposure was low. This was an a priori investigation of the possible effects of an exposure rather than a post hoc evaluation of a geographical area thought to have a high incidence of cancer
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