Abstract

Comprising 46 countries and a total population exceeding 1·1 billion people, sub-Saharan Africa faces a looming health crisis. The region has long suffered high morbidity and mortality driven primarily by infectious diseases, malnutrition, and poor maternal and child health, but is now also being afflicted by a rising incidence of non-communicable diseases, including cancer. This double burden of disease is a consequence of lifestyle and behavioural changes, a shift to an ageing population, genetics, infection, and environmental factors.

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