Abstract
Cancer is a deadly disease wherein the immune system is inefficient, resulting in malignant tumors that metastasize. An active and robust immune system is the body’s natural defense. Research efforts continue exploring alternative immunotherapies to fight cancer. This communication proposes non-infectious vaccines and hyper-allergenic skin creams to starve malignant tumors through immune metabolic interference.
Highlights
Is a malignant tumor evading your immune system? Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020 [1]
In an article published in Frontiers in Oncology (2021), titled "Repurposing Infectious Diseases Vaccines Against Cancer." the researchers write, “The recent approval of immunotherapies has rejuvenated this research area with reports of anti-tumor responses with existing infectious diseases vaccines used as such, either alone or in combination with immune checkpoint inhibitors” [13]
Live-attenuated vaccines contain a small amount of the weakened live virus, some patients should talk to their health care provider before receiving them, such as cancer patients with weakened immune systems [15]
Summary
Is a malignant tumor evading your immune system? Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020 [1]. For the millions of Americans diagnosed with cancer each year, the cost of treating the disease can be staggering [2]. Malignant tumors have atypical metabolism to satisfy an increased demand for energy and nutrients [3]. Cancer attrition immunotherapy proposes an “immune metabolic interference” mechanism to direct energy and nutrients away from malignant tumors. The major branches of adaptive immunity, cell-mediated and humoral, affect cytokine-mediated “reprogramming” of nutrient uptake and utilization to support the increased demands of adaptive immunity [4]. Cancer attrition immunotherapy is immunologically robust, metabolically expensive, innocuous, and financially inexpensive. A combination of FDA-approved vaccines and hyper-allergenic skin creams [5] stimulates adaptive immunity to promote cancer regression
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