Abstract

Canalicular adenoma (CA) is a benign salivary gland tumor that most commonly affects the upper lip of older patients. We report 2 additional cases of CA with unusual clinical and microscopic findings. Case 1 is a 76-year-old woman presenting a painless bluish nodule of fibrous consistency and 3-month duration, covered by a smooth surface with telangiectatic small vessels and located in the buccal mucosa. Case 2 is a 65-year-old woman referred for evaluation of an asymptomatic normal-colored nodule of 6 months' duration in the upper lip mucosa. Excisional biopsy was performed and microscopically both cases showed monomorphic epithelial ductal cells arranged in anastomosing cords within vascular stroma, confirming the diagnosis of CA. Interestingly, the second case exhibited exuberant secretory areas and clusters of foam cells. No recurrence was observed after 6 months of follow-up. Buccal mucosa location, bluish coloration, and exuberant secretory areas are unusual findings occasionally observed in CA.

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