Abstract
Canalicular adenoma is an uncommon benign salivary gland neoplasm that has a marked predilection for occurrence in the upper lip. It is composed of columnar cells arranged in ramification and interconnecting cords of single or double cell thick rows. The treatment consists of conservative surgical. In the present report, it is described a 75-year-old female patient presenting a nodular lesion in the upper lip. Surgical excision of the lesion was performed. The histopathologic findings were inconclusive, and it was raised the hypothesis of canalicular adenoma and basal cell adenoma. The immunohistochemistry study revealed that all cells in parenchyma were positive for cytokeratin-7 and negative for SMA. Thus, it established the diagnosis of canalicular adenoma. This lesion has an excellent prognosis after conservative surgical treatment. There was no recurrence after 1 year follow-up of our patient. Furthermore, immunohistochemical study is useful in separating these different entities.
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