Abstract
The American Migraine Prevalence and Prevention (AMPP) study is a prospective population-based study of nearly 24,000 adults with headache. The AMPP has identified individuals with both episodic and chronic migraine, and followed them for multiple years. Previous data from this study have shown that each year 2.5% of patients with episodic migraine transform into chronic migraine, that overuse of acute migraine medications may play a role in this transformation,1 and that chronic migraine is significantly disabling.2 In this issue of Neurology ®, Manack and colleagues3 use data from this study to describe the characteristics of patients who remit from chronic migraine (>15 headaches days per month) back to episodic headache or no headache. These investigators were able to follow 383 community patients with chronic migraine over a …
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