Can Vitamin C Prevent Complex Regional Pain Syndrome in Patients with Wrist Fractures?

Abstract

To The Editor: We read with interest and concern the article, “Navigated Total Knee Replacement. A Meta-Analysis” (2007;89:261-9) by Bauwens et al. We submitted a similar meta-analysis to The Journal of Bone and Joint Surgery over one year ago, which was appropriately rejected for publication because of the inclusion of data from abstracts and uncontrolled case series. The reviewers and editors also expressed concern that our finding of an advantage for navigated total knee arthroplasty compared with conventional total knee arthroplasty based on radiographic alignment end points needed to be balanced against the lack of evidence with regard to differences in cost-effectiveness, complication rates, and long-term outcomes between the two procedures. We were in the process of updating our meta-analysis in light of more recent publications (excluding data from abstracts and uncontrolled case series) when the study by Bauwens et al. was published. Having reviewed essentially the same database, we were perplexed by the authors' conclusion that “navigated knee replacement provides few advantages over conventional …