Abstract

To determine the ultrasonographic (US) features that could help to distinguish between parathyroid masses abuttingthe thyroid gland and thyroid masses extending into the parathyroid area. Two blinded readers retrospectivelyevaluated the US images of 76 histopathologically confirmed parathyroid masses abutting the thyroid gland and34 thyroid masses extending into the parathyroid area. Maximal diameter, transverse diameter/anterior-posterior diameter (T/AP) ratio, longitudinal diameter/AP diameter (L/AP) ratio, margin, shape, echogenicity, echotexture, and echogenic interfacewere evaluated and compared between the two groups. Echogenic interface (p<0.001) and L/AP ratio (p<0.001)were statistically significant US features that differentiated parathyroid and thyroid masses. Other US features did not showany significant differences between the two groups. Interobserver agreement was excellent for all US features. Sensitivity/specificity of the presence of echogenic interface and L/AP ratio >2.0 were 85.5%/100% and 43.2%/82.4% in distinguishingparathyroid from thyroid masses, respectively. The presence of an echogenic interface and L/AP ratio >2.0 wereuseful US features for differentiating parathyroid masses abutting the thyroid gland from thyroid masses extending into theparathyroid area.

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