Abstract

AimTo compare hemolysis marker levels of irradiated and non-irradiated packed red blood cells (PRBCs) after infusion by different neonates intravenous catheter. MethodExperimental study. Irradiated and non-irradiated PRBCs administered in vitro in peripheral intravenous catheter (PIVC),Umbilical (UC), and peripheral intravenous central catheter (PICC). Collected aliquots directly from PRBC bag, after filling the infusion system and catheter infusion. The hemolytic markers analyzed were: degree of hemolysis; hematocrit–Hct; total hemoglobin–THb; free hemoglobin–FHb; potassium– K; and lactate dehydrogenase–LDH. ResultsPVIC did not significantly influence hemolysis marker levels. The UC infusion influenced levels of FHb (p = 0.005), K (p = 0.001) and THb (p = 0.001); while PICC demonstrated significant effect on FHb (p = 0.010), degree of hemolysis (p = 0.026) and LDH (p = 0.050) levels in non-irradiated and irradiated PRBCs. ConclusionIn vitro infusion of irradiated and non-irradiated PRBCs resulted in significant changes in the levels of UC and PICC hemolysis markers, however, such levels do not contraindicate their use in neonatal transfusion.

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