Abstract
Objective : There is an increasing rate of ectopic pregnancy with the use of assisted reproductive techniques. There is currently no serum test to differentiate ectopic pregnancy from miscarriage. Early and accurate detection of ectopic pregnancy may prevent the development of complications. The aim of this study was whether the ratio of serum/curettage material hCG could provide us with reliable and early diagnosis in distinguishing miscarriage and ectopic pregnancies and also to measure the diagnostic accuracy rate of this method. A total of 24 patients were evaluated. Twelve of them were diagnosed as an ectopic pregnancy and 12 of them were diagnosed as a miscarriage. All the patients' diagnoses were confirmed pathologically. Non-of the patient had viable fetus. All participants underwent curettage protocol. Serum and curettage material were obtained at the same time. HCG measurements were done from blood and curettage material. Ratio of Blood/Curettage Material HCG provides fast and reliable results within a few hours with 91.7% accuracy rates. Ratio of blood/curettage material HCG can be used as a reliable method for differentiating ectopic pregnancy and miscarriage.
Highlights
Ectopic pregnancy (EP) refers to the implantation of a viable ovum outside the uterine corpus, which is a significant cause of maternal morbidity and mortality
In 8–31% of women who are Differentiating miscarriage & ectopic pregnancy admitted to a clinic for early pregnancy, sac may not be visualized by transvaginal sonography (TVS)
We prospectively studied 26 consecutive patients with miscarriages and EP presenting with positive β-hCG, abdominal pain, vaginal bleeding and history of amenorrhea who were admitted to our tertiary centre emergency clinic
Summary
Ectopic pregnancy (EP) refers to the implantation of a viable ovum outside the uterine corpus, which is a significant cause of maternal morbidity and mortality. In 8–31% of women who are Differentiating miscarriage & ectopic pregnancy admitted to a clinic for early pregnancy (hCG>5), sac may not be visualized by TVS These women are classified as having a “pregnancy of unknown location” (PUL).[3,4] In rare cases there is no evidence of trophoblastic tissue on ultrasound or at laparoscopy and the serum hCG levels are low and have reached a plateau (
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