Abstract
We appreciate Dr Fragasso's interest in our recent work.1 Fragasso et al. 2 showed in patients with coronary disease a lowered left ventricular filling rate 2 days after exercise that was no longer significantly different from baseline at 7 days. Whether this is sufficient to support the notion that exercise-induced myocardial ischaemia in patients with stable coronary artery disease causes sustained clinically significant diastolic dysfunction cannot be certain. Importantly, the 15 patients in Dr Fragasso's study had severe coronary disease as evidenced by …
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