Can meteorological factors forecast asthma exacerbation in a paediatric population?

Abstract

BackgroundAsthma exacerbations attended in emergency departments show a marked seasonality in the paediatric age. This seasonal pattern can change from one population to another and the factors involved are poorly understood. ObjectivesTo evaluate the association between meteorological factors and schooling with asthma exacerbations in children attended in the paediatric emergency department of a district hospital. MethodsWe conducted a retrospective review of the medical records of children 5–14 years of age attended for asthma exacerbations during a 4-year period (2007–2011). Climatic data were obtained from a weather station located very close to the population studied. The number of asthma exacerbations was correlated to temperature, barometric pressure, relative humidity, rainfall, wind speed, wind distance, solar radiation, water vapour pressure and schooling, using regression analyses. ResultsDuring the study period, 371 children were attended for asthma exacerbations; median age was eight years (IQR: 6–11), and 59% were males. Asthma exacerbations showed a bimodal pattern with peaks in spring and summer. Maximum annual peak occurred in week 39, within 15 days from school beginning after the summer holidays. A regression model with mean temperature, water vapour pressure, relative humidity, maximum wind speed and schooling could explain 98.4% (p<0.001) of monthly asthma exacerbations. ConclusionsThe combination of meteorological factors and schooling could predict asthma exacerbations in children attended in a paediatric emergency department.