Can inflammatory markers such as lymphocyte to C-reactive protein ratio and hemoglobin, albumin, lymphocyte, and platelet score predict complications after loop ileostomy closure?

Abstract

Aim: This study aims to investigate whether inflammatory biochemical markers such as hemoglobin, albumin, lymphocyte, platelet scores (HALP), and lymphocyte-C-reactive protein ratio (LCR) can predict complications after ileostomy closure. Methods: Eighty-five patients who underwent loop ileostomy closure were included in this retrospective study. Alongside the patient’s demographic data, surgical data, histopathology results, and biochemistry data were recorded. Complications that occurred within the first 30 days after surgery were evaluated using the Clavien-Dindo classification. Inflammation markers such as HALP and LCR were obtained using biochemical parameters. Results: The rate of mild complications (Clavien-Dindo I and II) was 27%, while the rate of severe complications (Clavien-Dindo III and IV) was 12.94%. A statistically significant correlation was found between the development of early complications and levels of albumin, lymphocyte, neutrophil, and C-reactive protein (CRP) (p