Abstract

Undernutrition, such as stunting and underweight, is a major public health concern, which requires multi-sectoral attention. Diet plays a key role in growth and should optimally supply all required nutrients to support the growth. While millets (defined broadly to include sorghum) are traditional foods, and climate smart nutritious crops, which are grown across Africa and Asia, they have not been mainstreamed like rice, wheat, and maize. Diversifying staples with millets can potentially provide more macro and micro nutrients, compared to the mainstream crops. However, there is little known scientific evidence to prove millets’ efficacy on growth. Therefore, a systematic review and meta-analysis was conducted to collate evidence of the benefits of millets in improving the growth of children. Eight eligible randomized feeding trials were included in the meta-analysis. Results from the randomized effect model showed a significant effect (p < 0.05) of millet-based diets on mean height (+28.2%) (n = 8), weight (n = 9) (+26%), mid upper arm circumference (n = 5) (+39%) and chest circumference (n = 5) (+37%) in comparison to regular rice-based diets over for the period of 3 months to 4.5 years, which was based on largely substituting rice with millets. When an enhanced and diverse diet was served, replacing rice with millet had only minimal growth improvement on chest circumference (p < 0.05). The quality assessment using GRADE shows that the evidence used for this systematic review and meta-analysis had moderate quality, based on eight scoring criteria. These results demonstrate the value of adding millet as the staple for undernourished communities. Further understanding of the efficacy of millets on growth in a wider range of diets is important to develop appropriate dietary programs and improve the nutritional status of various age groups across Africa and Asia.

Highlights

  • Undernutrition, especially stunting, underweight, and wasting, is a major global crisis

  • The protocol for this systematic review and meta-analysis was registered retrospectively in the online registration platform, with the unique identification number (UIN), Reviewregistry1180, which can be accessed by browsing the registry of systematic review/meta-analyses with UIN

  • The difference in differences (DID) was positive and significant (p < 0.05) with high heterogeneity (I2 = 94%) among studies and a pooled Standard Mean Difference (SMD) of 2.92

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Summary

Introduction

Undernutrition, especially stunting, underweight, and wasting, is a major global crisis. Undernutrition puts children in greater risk of susceptibility to infections, increases the frequency and severity of such infections, and delays recovery. 45% of global deaths among children under five are linked to undernutrition [2], which is common in low- and middle-income countries. It is noteworthy, over a half of the stunted children under five years live in Asia, and more than one-third in Africa, while more than two-thirds of the wasted children live in Asia and more than one-quarter in Africa (UNICEF/WHO/World bank, 2019).

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