Abstract

Can existing unrelated vaccines boost a COVID-19 vaccine prime?

Highlights

  • Commentary—The development of new specific vaccines against COVID-19 has occurred as the US program name promised, at “warp speed,” and emergency use authorization has led to vaccine rollout around the world

  • Vaccination schedules are designed around specific trials and regimens, and the currently authorized COVID-19 vaccines have been developed with a booster dose scheduled a certain time after the initial prime

  • Economic and logistical considerations have motivated studies to assess one-dose compared to two-dose vaccines, and at least one ‘one-dose’ COVID-19 vaccine is under development

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Summary

Introduction

Can existing unrelated vaccines boost a COVID-19 vaccine prime? Commentary—The development of new specific vaccines against COVID-19 has occurred as the US program name promised, at “warp speed,” and emergency use authorization has led to vaccine rollout around the world. Most vaccinations require one or more “boosts” to reach a level of memory cells needed to provide protection against infection.

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Conclusion
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