Abstract

Successful implantation requires synchronous development of the embryo and endometrium. Euploid embryos fail to implant in about ⅓ of IVF cycles, which may be attributable to a non-receptive endometrium. The endometrial receptivity array (ERA) has emerged as a diagnostic tool to identify receptive endometrium and to guide timing of embryo transfer. While studies have shown the utility of ERA testing in a natural cycle, the impact of endometrial stimulation with exogenous estrogen (E) and progesterone (P) on ERA results are not well understood.

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