Abstract
To understand how much screening endoscopy (sigmoidoscopy or colonoscopy) reduces colorectal cancer incidence and mortality, there has been no evidence from a randomised trial of sufficient size and duration to draw strong conclusions. The reduction in colorectal cancer mortality of 60–70% for lesions within reach of the sigmoidoscope is based on case-control research.1 The reduction in the incidence of colorectal cancer of 76–90% for colonoscopy is based on a study that used historical controls,2 a design that can inflate estimates of benefit.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
