Abstract
Can Antibodies Protect Us Against Cardiovascular Disease?
Highlights
Antibodies represent one the most effective tools to fight invading pathogens used by the immune system
In the present issue of EBioMedicine, Khamis and co-workers report that subjects that go on to suffer from coronary heart disease (CHD, including myocardial infarction, death from coronary heart disease and coronary revascularization) are characterized traditional risk factors such as smoking, hypertension and hypercholesterolemia and by lower levels of total IgG and to some extent lower levels of IgM (Khamis et al, 2016)
The association between low IgG levels and CHD remained when controlling for the variables used in the Framingham risk score and inclusion of IgG improved risk prediction and decreased misclassification into low and high risk individuals
Summary
Antibodies represent one the most effective tools to fight invading pathogens used by the immune system. Article history: Received 27 June 2016 Accepted June 2016 Available online June 2016 Some antibodies bind self-antigens helping to clear away apoptotic cells and other debris providing important house-keeping functions.
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