Abstract

PurposeTo test whether or not adults assign the same values to hypothetical health states that describe health in adults as when those same descriptions refer to the health of a child.MethodsA two-part self-completion questionnaire was designed in which respondents were asked firstly to rate a fixed set of EQ-5D-Y health states on a 0–100 visual analogue scale as if they themselves were in these states. Two versions of the questionnaire were produced each with a different second part. One version instructed respondents to value the same states but to imagine them describing another adult. The second version required respondents to value these states as if they applied to a 10-year-old child. Questionnaires were distributed to adults recruited in three countries (Germany, Spain and England) using convenience sampling methods.ResultsA total of 1085 questionnaires were completed. Despite some significant differences in the characteristics of the achieved samples in the three countries involved, the rank order of health states was largely consistent across each adult/child reference perspective. In all countries, the mean values were lower when health states described children rather than adults. Significant differences were found for 16/24 states when values for those states applied to adult respondent themselves were compared with the values for those states applied to a 10-year-old child. A near-uniform pattern was found across all three countries in which health state values for children were found to be lower than for adults.ConclusionsValues for health states when ascribed to adults are higher than when those same states are associated with children. Were EQ-5D-3L values for adults applied to EQ-5D-Y health states, then this would effectively lead to an misrepresentation of the value assigned to a health status in children.

Highlights

  • The measurement of health benefit is arguably the central issue in any evaluation of healthcare interventions

  • A two-part self-completion questionnaire was designed in which respondents were asked firstly to rate a fixed set of EQ-5D-Y health states on a 0–100 visual analogue scale as if they themselves were in these states

  • The situation is far less clear when it comes to the measurement of health benefits in children where the development of appropriate metrics has significantly lagged behind the corresponding effort directed towards developing adult measures

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Summary

Introduction

The measurement of health benefit is arguably the central issue in any evaluation of healthcare interventions. For the evaluation of adult interventions, there is a small, well-defined set of generic index measures that are in widespread use, foremost amongst these being EQ-5D [1]. The situation is far less clear when it comes to the measurement of health benefits in children where the development of appropriate metrics has significantly lagged behind the corresponding effort directed towards developing adult measures. This differential can in part be attributed to wider and more deep-rooted issues that have obstructed progress in this specialist research field. The complexity of developing generic measures for use with children and young people has parallels in long-standing issues that

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