Abstract
Despite significant advances in neurocritical care, it remains difficult to precisely measure the extent of neurological injury in patients affected by stroke, trauma, or cardiac arrest. In the intensive care unit the extent of primary and secondary injury often eludes clinicians, making prognostication imprecise and difficult. Derwall and colleagues present their findings on the dynamics of serum S-100B protein levels in out-of-hospital cardiac arrest survivors. Their study suggests that elevation of S-100B reflects the severity of the primary hypoxic-ischemic insult.
Highlights
The first decade of the 21st century has witnessed explosive growth in therapies for the critically ill neurological patient
It remains difficult to precisely measure the extent of neurological injury in patients affected by stroke, trauma, or cardiac arrest
In a recent issue of Critical Care, Derwall and colleagues [1] present their findings on the dynamics of serum S-100B protein levels in a prospectively studied cohort of out-ofhospital cardiac arrest (OHCA) survivors
Summary
The first decade of the 21st century has witnessed explosive growth in therapies for the critically ill neurological patient. Others, such as hypothermia for the treatment of brain injury after cardiac arrest, have multiple additive and synergistic mechanisms of action that culminate in the protection of nervous tissue. It remains difficult to precisely measure the extent of neurological injury in patients affected by stroke, trauma, or cardiac arrest.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
