Abstract
A perceived disadvantage of fine needle aspiration biopsy is that aspiration biopsy cytology cannot be correlated with tissue grading systems based on tissue patterns of prostate carcinoma. We feel that it is possible to predict tissue patterns of prostate carcinoma and to estimate Gleason's scores in aspiration biopsy specimens. Cytologically, prostate carcinomas may be reduced to those with glands, cribriform patterns, or undifferentiated solid or discohesive structures. Tumor grading based on patterns of prostate carcinoma may have significant impact on judging patient prognosis and on determining optimum patient therapy by allowing the urologist to apply the vast bank of existing data based on tissue studies to the interpretation of material obtained by fine needle aspiration biopsy of the prostate gland.
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