Abstract
Rats received a diet containing a Cabinding ion exchanger at a dose of 30 and 90 g/kg diet, respectively. Following 10 days of oral administration there was a dose dependent increase in urinary cAMP excretion. However, after 20 days treatment the measured cAMP content in the urine was no longer different from control values. The results suggest that urinary cAMP excretion in the rat is only of value as an indication of acute changes in PTH-activity.
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