Calorimetric approach to establishing thermokinetics for cosmeceutical benzoyl peroxides containing metal ions

Abstract

Cosmeceutical products have improved over the years; however, the explosions and fire accidents in cosmeceutical factories worldwide have not ceased. Literature researches on this genre of potential risk have been seldom published. Cosmeceutical benzoyl peroxide (CBPO) is usually used on facial products, especially for acne treatment. The thermal stability of CBPO with additions and calorimetric technology is utilized to obtain the thermal stability and reaction characteristics. Depending on the experimental thermal stability parameters, apparent activation energy was calculated by various integral and differential kinetic models. Uniting the isoconversional kinetic analysis and numerical simulation of the isothermal condition can better realize the decomposition characteristics and potential process risk. Dozens of milligrams of CBPO were dunked with 10,000 ppm of Cu, Fe, and Zn to inspect the exothermal behavior. The findings can be a reference for the essential safety parameters and customer safety design for the database.