Callosal Transfer Test Performance in Patient with Multiple Sclerosis: A Case Report

Abstract

Patient (P) female, 23, consistent right-hander was diagnosed as having multiple sclerosis at the onset of clinical symptoms (loss of sensation in the left limb and left part of the face). MRI revealed demyelination in cerebellar region, intratentorial white matter and tissue adjacent to the fourth ventricle, as well as demyelinated plagues localized in the rostrum, truncus and splenium of corpus callosum. One year after, aggravation of clinical symptoms (loss of sensation in the right limb and in the right part of the face, difficulty in holding as well as recognizing things, discoordination of movements and occasional diplopia) was registered. Patient was tested on callosal interhemispheric transfer of information after the spontaneous resolve of most of symptoms. At that period, patient experienced paresthesia in the upper limb when bending the neck. Tests on finger cross- localization, crossmatching of objects, drawing to dictation, simultaneous drawing with both hands, reading words perceived by “non-verbal” right hemisphere and line bisection were administered. Patient was found successful in performing all tests on interhemispheric transfer of information, suggesting the callosal system of study participant efficient in interhemispheric communication.