Call for Special Issue Papers: Special Issue on High-throughput Technologies for the Discovery and Development of Chemical Probes and Pharmacological Tools

Abstract

ASSAY and Drug Development TechnologiesVol. 19, No. 7 Call For PapersFree AccessCall for Special Issue Papers: Special Issue on High-throughput Technologies for the Discovery and Development of Chemical Probes and Pharmacological ToolsDeadline for Manuscript Submission: November 1, 2021Guest Editors: Milka Kostic and Bruce J. MelanconGuest Editors: Milka KosticDana-Farber Cancer Institute, Boston, MA, USASearch for more papers by this author and Bruce J. MelanconVanderbilt University School of Medicine, Franklin, TN, USASearch for more papers by this authorPublished Online:4 Oct 2021https://doi.org/10.1089/adt.2020.29095.cfp2AboutSectionsPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail Pharmacological and chemical probes are foundational tools for asking basic biological and translational questions. They complement genetic strategies, such as CRISPR and RNA interference technologies. Together, these strategies enable biologist and clinician scientist to advance biomedical research and accelerate discovery of the next generation of therapeutics.This premier special issue of the series focuses on emerging high-throughput technologies that are critical for rapid, reliable, and reproducible discovery and/or validation of chemical probes and pharmacological tools (inhibitors, agonists, antagonists, degraders (PROTACs and molecule glue compounds, natural products, and similar).Some of the assays and technologies of interest include: (a) phenotypic, fragment-based or target-based screening for small molecule ligand discovery; (b) high-throughput biochemical, biophysical. And cell-based methods that accelerate probe characterization; (c) chemoproteomic and proteomic methods for probe discovery and validation; (d) computer-based methods if supported by extensive wet-lab follow up. We are also interested in strategies for screening library design and development, as well as advanced assays for target validation.Special Issue Editors, Milka Kostic, PhD, Dana-Farber Cancer Institute, and Bruce J. Melancon, PhDVanderbilt University, School of Medicine, will consider articles from the full breadth of research in the field from original research papers, reviews, and methods papers, to perspectives, profiles, commentaries, and exemplary front matter.Areas of interest include, but are not limited to: Phenotypic, fragment-based or target-based screening for small molecule ligand discoveryHigh-throughput biochemical, biophysical, and cell-based methods that accelerate probe characterizationChemoproteomic and proteomic methods for probe discovery and validationComputer-based methods, if supported by extensive wet-lab follow upContributions will receive prompt and thorough peer review, feedback, and decision. Please refer to our Instructions for Authors before submitting your manuscript for consideration. Authors are encouraged to evaluate ideas directly with Milka Kostic, PhD (Milka_Kostic@DFCI.HARVARD.EDU).ASSAY and Drug Development Technologies provides access to novel techniques and robust tools that enable critical advances in early-stage screening. This research published in the Journal leads to important therapeutics and platforms for drug discovery and development. This reputable peer-reviewed journal features original papers application-oriented technology reviews, topical issues on novel and burgeoning areas of research, and reports in methodology and technology application. Please visit our website at www.liebertpub.com/adt to view our Information for Authors.Editorial or technical questions?Contact Taylor Bowen (assay_eo@liebertpub.com)Visit the Instructions for Authors:www.liebertpub.com/adtSubmit your paper for peer review online:https://mc.manuscriptcentral.com/assayFiguresReferencesRelatedDetails Volume 19Issue 7Oct 2021 InformationCopyright 2021, Mary Ann Liebert, Inc., publishersTo cite this article:Guest Editors: Milka Kostic and Bruce J. Melancon.Call for Special Issue Papers: Special Issue on High-throughput Technologies for the Discovery and Development of Chemical Probes and Pharmacological Tools.ASSAY and Drug Development Technologies.Oct 2021.403-404.http://doi.org/10.1089/adt.2020.29095.cfp2Published in Volume: 19 Issue 7: October 4, 2021Online Ahead of Print:August 27, 2021PDF download