Abstract
An overview is presented of the different aspects of the role of analytical chemistry in process monitoring and control. On-line monitoring is currently the most attractive option in this area, especially with unsegmented-flow techniques. In addition to allowing automation of these systems, the variety of ways in which calibration and recalibration can be performed allows their adaptation to any situation by using extremely simple, home-made manifolds. The most relevant designs are presented and critically discussed in this paper.
Highlights
The analytical chemist’s responsibility has been limited to the laboratory
There are two general approaches to it which depend on the location of the measuring instrument and the degree of human participation: (a) Traditional off-line monitoring, in which the conventional instruments are all in the laboratory, and the human operators are highly involved in the process
In off-line monitoring, sampling and sample transport are performed with a high degree ofhuman participation
Summary
The analytical chemist’s responsibility has been limited to the laboratory. Analytical chemists are currently involved in such tasks outside the laboratory as sampling, and establishing a rapport with other scientists/ technicians to promote, perform and evaluate basic and applied developments. One of these tasks, process control, is a target at which the endeavours of analytical chemists should be aimed in the forthcoming years. In the USA the CPAC (Center for Process Analytical Chemistry) has recently been set up supported by the National Science Foundation and aimed at the development of analytical methods for direct integration into the production process and coupling with chemometric techniques [1]. The issues involved in the basic research on process analysis and control carried out at the CPAC are: NON- INVASIVE
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
