Abstract
Caliber persistent labial artery (CPLA) consists in a dilated portion of the main branch of the labial artery without loss of size. The aim of this study is to report a case of a patient diagnosed with CPLA in the upper lip, emphasizing unusual histopathological and immunohistochemical findings. A 67-year-old female patient with complaint of a pulsating upper lip lesion without painful symptomatology. Under a clinical diagnosis of CPLA, and considering that the patient was edentulous and used a total prosthesis, an excisional biopsy of the lesion was performed to avoid future traumas in the region and consequently possible exuberant local bleeding. At anatomopathological examination structures suggestive of lymphoid follicles and germinal centers were visualized. Immunohistochemistry showed positivity for CD20, CD68, desmin and CD34 and negativity for CD4. The patient did not have a history of allergies, cardiovascular, rheumatic or systemic diseases that could justified the findings. The case presents unusual histopathological structures, evidencing the necessity of more studies about this pathology so scarce in the literature.
Highlights
Caliber persistent labial artery (CPLA) consists in a dilated portion of the main branch of the labial artery that penetrates the submucosal tissue without loss of caliber [1,2]
The aim of this study is to present the case report of a patient diagnosed with a caliber persistent artery in the upper lip reporting unusual histopathological and immunohistochemical findings for the first time
It has been suggested that the development of this abnormality in the lower lip is due to the great caliber of the inferior alveolar artery [4,6]
Summary
Caliber persistent labial artery (CPLA) consists in a dilated portion of the main branch of the labial artery that penetrates the submucosal tissue without loss of caliber [1,2]. The caliber persistent labial artery has been described in gastrointestinal tract sites, such as the stomach and jejunum [1] This condition is more common in the lower (about 80% of lesions) and upper lips, and may appear on the palate [2,5,6,7]. Conservative methods are usually the first choice, and the surgical approach is recommended only when the aesthetic impact is very important to the patient or when other difficulties apply [7] In this context, the aim of this study is to present the case report of a patient diagnosed with a caliber persistent artery in the upper lip reporting unusual histopathological and immunohistochemical findings for the first time. A literature review on CPLA is presented
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