Calgary score and modified Calgary score in the differential diagnosis between neurally mediated syncope and epilepsy in children.

Abstract

To evaluate the value of Calgary score and modified Calgary score in differential diagnosis between neurally mediated syncope and epilepsy in children. 201 children experienced one or more episodes of loss of consciousness and diagnosed as neurally mediated syncope or epilepsy were enrolled. Calgary score, modified Calgary score and receiver-operating characteristic curve were used to explore the predictive value in differential diagnosis. There were significant differences in median Calgary score between syncope [-4.00 (-6, 1)] and epilepsy [2 (-3, 5)] (z=-11.63, P<0.01). When Calgary score ≥1, the sensitivity and specificity of differential diagnosis between syncope and epilepsy were 91.46 and 95.80%, suggesting a diagnosis of epilepsy. There were significant differences in median modified Calgary score between syncope [-4.00 (-6, 1)] and epilepsy [3 (-3, 6)] (z=-11.71, P<0.01). When modified Calgary score ≥1, the sensitivity and specificity were 92.68 and 96.64%, suggesting a diagnosis of epilepsy. The sensitivity and specificity of modified Calgary score and Calgary score did not show significant differences (P>0.05). Calgary score and modified Calgary score could be used to differential diagnosis between syncope and epilepsy in children.