Abstract
Methods for covalent and non-covalent functionalization of single-walled carbon nanotubes (CNTs) with folic acid and their spectroscopic characterization are described. The irradiation of NTC-AF aqueous solutions with IR generates a heating effect that it dependent on the concentration of solution, the beam power and the type of interaction between folic acid and NTC. The control experiments show that the increase in temperature is only due to NTC. Preliminary biological studies indicate an internalization of the bioconjugate in THP-1 and infected cells with Leishmania parasites, showing that the thermal effect generated by the IR illumination can reduce the population of infected cells. © 2014. Acad. Colomb. Cienc. Ex. Fis. Nat. All rights reserved.
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