Abstract
The Nottingham Prognostic Index (NPI) is a widely used prognostic tool for stratification of breast cancer patients. Aim of this study was to compare the Nottingham Prognostic Index (NPI) score with prognosis of breast cancer and clinicopathological prognostic parameters. In the present study, One hundred twenty five breast cancer patients ranging in age from <40 to ≥60 years were evaluated. Breast cancer patients were stratified into good, moderate and poor prognosis. 46.4% frequency of patients was found with moderate prognosis, 36.8%, 16.8% frequency of patients was found in poor and good prognosis group respectively. Majority of the young patients were in poor prognosis group. Breast cancer patients with grade III showed the poor prognosis as compared with grade I and II. Poor prognosis was in positive correlation with tumor size and lymph node status. In conclusion, further combined prognostic index validation strategies are required which should be simple, accurate and have independent value as assessed by multivariate analysis.
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