Abstract
1. The rate of calcium uptake and the amount of calcium stored by skeletalmuscle microsomes were remarkably dependent on temperature in the presenceof oxalate, while they were scarcely affected by temperature in the absenceof oxalate. The activation energy in the presence and absence of oxalate wasabout 20, 000cal/mole and 4, 500cal/mole, respectively.. The rate of calcium uptake increased with increasing the amount of micro-somes in the presence and absence of oxalate. However, the saturation timewas 2 minutes even in 1mg/ml of microsomes in the presence of oxalate.3. The amount of calcium stored increased with increasing calcium concentration in the presence and absence of oxalate. However, the relationship of hem did not coincide with the theoretical dissociation curve.4. The rate of calcium uptake in the presence of oxalate decreased withincreasing calcium concentration.
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