Abstract
In three studies the effects of changes in dietary sodium, chloride and calcium levels on urinary excretion and tissue levels of sodium, potassium, calcium, phosphorus and magnesium were evaluated. When rats were fed moderate (5000 μg Ca/g) levels of calcium, the addition of 4600–6300 μg Na/g to the basal diet as sodium chloride or sodium bicarbonate increased urinary volume. However, when rats were fed high (10,000 μg Ca/g) levels of calcium, only the addition of sodium chloride increased urinary volume. Rats fed excess sodium excreted more sodium in the urine. However, rats fed excess sodium as sodium chloride tended to excrete more sodium, potassium, calcium, phosphorus and magnesium in urine than rats fed equal amounts of sodium as sodium bicarbonate. Despite the many effects of the dietary treatments on urinary excretion, they had no effects on bone, muscle or kidney levels of sodium, potassium and phosphorus; on bone or muscle levels of calcium; or on muscle and kidney levels of magnesium. The effects of the treatments on bone magnesium levels were not consistent among studies.
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