Abstract
By virtue of their biological simplicity and widespread availability, platelets frequently have been used as a model system to study signal transduction. Such studies have revealed that changes in intracellular free calcium concentration are central to platelet functioning. The following article reviews current concepts of platelet structure and function, with particular emphasis on the mechanisms involved in platelet Ca 2+ signalling.
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Schedule a callMore From: Pharmacology and Therapeutics: Part C: Clinical Pharmacology and Therapeutics
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