Abstract

In a group of 12 patients with steatorrhea secondary to various etiologies, defective calcium absorption and negative calcium balance occurred in all patients with biochemical osteomalacia. Losses of body calcium resulted from obligatory endogenous fecal losses. High endogenous fecal calcium values appeared to be due to increased digestive juice secretions as well as defective reabsorption. Bone calcium turnover in osteomalacia varied from below to well above the normal range in agreement with reported data on bone biopsy studies. Markedly elevated bone calcium accretion rates were found in idiopathic steatorrhea alone and were associated with advanced bone disease.

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