Abstract
Calcium entry blocking activities of adenosine and its potentiating drugs, dilazep, lidoflazine and dipyridamole, were studied in potassium (100 mM)-depolarized guinea pig taenia coli, and compared with nifedipine, verapamil and diltiazem. The potency ratio of calcium entry blocking effect of nifedipine, diltiazem, lidoflazine and dilazep to verapamil was 158.5, . 1 1.1 , 1 15.8 and 1 81.3 , respectively. Dipyridamole and adenosine had negligible calcium entry blocking effects.
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