Abstract
The density distribution associated with two characteristic equatorial reflections of the X-ray diagram indicates a movement of myosin cross-bridge towards the lattice position occupied by the actin. The extent of this mass transfer depends on the concentrations of ATP and Ca ++ in the medium. As cross-bridges are still moving away from the myosin filament backbone in fibres stretched to a sarcomere length where the two sets of filaments no longer overlap, simply on adding low levels of Ca ++ ions, this suggests a Ca ++-sensitive regulatory system on the myosin.
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