Abstract
Combination topical corticosteroids and vitamin D analog treatments for nail psoriasis are widely used in cream and ointment vehicles, but patients may prefer a foam vehicle due to ease of application and favorable cosmetic appearance. Calcipotriene 0.005%/betamethasone dipropionate 0.064% (Cal/BD) aerosol foam is an FDA approved therapy for plaque psoriasis, but may also be an effective treatment for nail psoriasis in a novel aerosol foam. We present a case series of 3 patients with mild to moderate nail psoriasis who responded positively to treatment with Cal/BD aerosol foam applied 1-2 times daily to affected nails for at least 6 weeks. Reduction of nail plate surface abnormalities and a decrease in inflammation of the nail folds were assessed with clinical evaluation and dermoscopy, and documented with serial photography. While further research on the efficacy and safety of Cal/BD aerosol foam as a treatment for nail psoriasis is needed, this report suggests its potential as a combination topical vitamin D analogue and high potency steroid in a foam vehicle.
Highlights
An estimated 80-90% of psoriasis patients develop nail involvement, leading to decreased quality of life secondary to pain, activity restriction, and an increased risk of anxiety and depression.[1]
Though combined approaches with topical vitamin D analogues and steroids as creams and ointments have been well-documented as effective treatments for mild psoriasis of the nail, there is minimal literature regarding the use and efficacy of calcipotriene/betamethasone dipropionate in a foam vehicle.[3,4]
0.005%/betamethasone dipropionate 0.064% (Cal/BD) aerosol foam is indicated for the treatment of plaque psoriasis; we report our experience utilizing it as a treatment for psoriasis of the nail
Summary
Calcipotriene 0.005%/Betamethasone Dipropionate 0.064% Foam as a Treatment for Nail Psoriasis: A Case Series. Shifa Akhtar[1], BS, Mariana Perez[1], BA, Jessica Sharma[1], BS, Agnese Canazza[2], Martin Zaiac[1,2], MD
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
