Calcinosis, Varioliform Gastritis, and Bleeding

Abstract

Gray et al1Gray M. et al.Clin Gastroenterol Hepatol. 2014; 12: xxiiGoogle Scholar attributed their patient's gastric bleeding to mucosal calcinosis associated with advanced renal disease. The endoscopic appearance of the gastric lesions resembles antral varioliform gastritis, which has a variable histology2Haot J. et al.Gut. 1990; 31: 282-285Google Scholar and can occur with similar duodenal lesions,3Haot J. et al.Gut. 1988; 29: 1258-1264Google Scholar as they depicted. In addition, 3 reported patients with this disorder had acute or occult bleeding.4Green P.H. et al.Am J Gastroenterol. 1982; 77: 543-547Google Scholar Therefore, it seems possible that varioliform gastritis had an etiologic role in their patient's bleeding. Gastric Mucosal Calcinosis: A Rare Cause of BleedingClinical Gastroenterology and HepatologyVol. 12Issue 3PreviewA 52-year-old man with end-stage renal disease on hemodialysis presented with coffee-ground emesis and black stools. The physical examination revealed pale conjunctivae but was otherwise unremarkable. The laboratory analysis was significant for hemoglobin 4.4 g/dL, creatinine 7.8 mg/dL, and normal calcium and phosphorus (8.7 mg/dL and 2.5 mg/dL, respectively). The esophagogastroduodenoscopy revealed multiple smooth, nonbleeding nodules measuring 3–5 mm in diameter, extending radially in linear rows throughout the antrum with an overlying clot (Figure A). Full-Text PDF